E-4997 Erlotinib, Free Base, >99%

Synonyms : [CP-358774] [OSI-774] [Ro 50-8231]

Related Terms : [Tarceva]

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  • 500 mg
  • 37
  • 30
  • 27
  • 4,100
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  • 1 g
  • 48
  • 40
  • 35
  • 5,300
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  • 2 g
  • 72
  • 60
  • 52
  • 8,000
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  • 5 g
  • 136
  • 113
  • 100
  • 15,100
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  • 10 g
  • 238
  • 198
  • 175
  • 26,400
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  • M.W. 393.44
  • C22H23N3O4
  • [183321-74-6]
  • M.I. 14: 3672

Storage: Store at or below -20 ºC. Solubility: Soluble in DMSO at 100 mg/mL; soluble in ethanol at 10 mg/mL with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-20 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility. Disposal: A.

Certificate of Analysis

  • This is the free base form of erlotinib; please see our product Erlotinib, Hydrochloride Salt, Cat. No. E-4007, for further technical information. The hydrochloride salt form of erlotinib, not the free base, is used in the erlotinib formulation for use in humans.
  • Erlotinib (as the hydrochloride salt) is the active ingredient in the drug product sold under the trade name Tarceva®. This drug has been approved in at least one country for use in patients with pancreatic cancer, non-small cell lung cancer and several other types of cancer. NOTE: THE ERLOTINIB, FREE BASE RESEARCH COMPOUND SOLD BY LC LABORATORIES IS NOT TARCEVA®, AND IS NOT FOR HUMAN USE.
  • This erlotinib product is the free base, whose CAS number is given above. The CAS number of the hydrochloride salt is 183319-69-9.
  • Related CAS numbers: 248594-19-6 for erlotinib mesylate.
  • Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.
  • This product is offered for R&D use in accordance with (i) 35 USC 271(e)+A13(1) in the U.S.; (ii) Section 69.1 of Japanese Patent Law in Japan; (iii) Section 11, No. 2 of the German Patent Act of 1981 in Germany; (iv) Section 60, Paragraph 5b of the U.K. Patents Act of 1977 in the U.K.; (v) Sections 55.2(1) and 55.2(6) and other common law exemptions of Canadian patent law; (vi) Section 68B of the Patents Act of 1953 in New Zealand together with the amendment of same by the Statutes Amendment Bill of 2002; (vii) such related legislation and/or case law as may be or become applicable in the aforementioned countries; and (viii) such similar laws and rules as may apply in various other countries.
  • Not available in some countries; not available to some institutions; not available for some uses.
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