R-1234 Roscovitine, Free Base, >99%

Synonyms : [CYC202]

Related Terms : [Seliciclib]

  • Size
  • US $
  • £
  • ¥
  • 10 mg
  • 49
  • 45
  • 38
  • 7,400
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  • In stock
  • 25 mg
  • 67
  • 61
  • 53
  • 10,200
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  • In stock
  • 50 mg
  • 128
  • 117
  • 101
  • 19,400
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  • 100 mg
  • 169
  • 155
  • 134
  • 25,600
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  • 200 mg
  • 224
  • 206
  • 177
  • 34,000
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  • 300 mg
  • 294
  • 270
  • 233
  • 44,600
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  • 1 g
  • 649
  • 597
  • 515
  • 98,500
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  • 2 g
  • 1,110
  • 1,022
  • 881
  • 168,400
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  • In stock
  • 5 g
  • 1,975
  • 1,818
  • 1,568
  • 299,700
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  • In stock

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  • M.W. 354.45
  • C19H26N6O
  • [186692-46-6]
  • M.I. 14: 10240

Storage: Store at or below -20 ºC. Solubility: Prepare initial stock solutions in DMSO (soluble at 200 mg/mL) or ethanol (soluble at 200 mg/mL) for in vitro use; solubility in water is low. Appearance: White to off-white powder. Disposal: A.

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View the SDS for this product

  • Roscovitine is a potent inhibitor of p34cdc2 (IC50 = 0.2 µM). Also inhibits p33cdk2 and p33cdk5. Havlicek, L., et al. "Cytokinin-derived cyclin-dependent kinase inhibitors: synthesis and cdc2 inhibitory activity of olomoucine and related compounds." J. Med. Chem. 40: 408-412 (1997).
  • NOTE: The word "Roscovitine" inherently means the R-isomer.
  • Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.
  • This product is offered for R&D use in accordance with (i) 35 USC 271(e)+A13(1) in the U.S.; (ii) Section 69.1 of Japanese Patent Law in Japan; (iii) Section 11, No. 2 of the German Patent Act of 1981 in Germany; (iv) Section 60, Paragraph 5b of the U.K. Patents Act of 1977 in the U.K.; (v) Sections 55.2(1) and 55.2(6) and other common law exemptions of Canadian patent law; (vi) Section 68B of the Patents Act of 1953 in New Zealand together with the amendment of same by the Statutes Amendment Bill of 2002; (vii) such related legislation and/or case law as may be or become applicable in the aforementioned countries; and (viii) such similar laws and rules as may apply in various other countries.
  • Not available in some countries; not available to some institutions; not available for some uses.
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