Thursday 19 May 2022 - 05:39
In Business 42 Years - Since 1980
Reminder: Genuine LC Laboratories® brand PMA, which we have been manufacturing in the U.S. for more
than 40 years, is available directly from us: Cat No. P-1680 Phorbol 12-Myristate 13-Acetate, >99.5%.
Our PMA is also available from our >50 U.S. and international distributors, and from more than a dozen
major biochemical reagent "resellers" (who sell our PMA under their own brand names and labels)
FREE SHIPPING TO THE U.S. AND 32 OTHER COUNTRIES! [Read more].
C-3987 Calyculin A, >98%
- Size
- US $
- €
- £
- ¥
- 25 µg
- 69
- 65
- 55
- 8,900
- In stock
- 50 µg
- 124
- 117
- 99
- 16,000
- In stock
- 100 µg
- 220
- 209
- 177
- 28,400
- In stock
- 300 µg
- 582
- 553
- 469
- 75,200
- In stock
- 1 mg
- 1,675
- 1,592
- 1,350
- 216,600
- In stock
Note: Our Euro, Pound, and Yen prices are revised regularly to account for currency exchange rate fluctuations.
- M.W. 1009.17
- C50H81N4O15P
- [101932-71-2]
- M.I. 14: 1724
Special Hazard: TUMOR PROMOTER. Gloves and mask should be worn when using this compound. Care must be taken to prevent contact through all routes of exposure.
Storage: Store at or below -20 ºC in the dark. Solubility: Soluble in DMSO and ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 1-10 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility. Disposal: A.
- LC Labs is the primary worldwide source of Calyculin A for laboratory research
- > 40 distributors and resellers worldwide offer our Calyculin A
- Thousands of labs have used our Calyculin A
- Very potent inhibitor (Ki = ca. 0.1 nM) with high specificity for the PP-1 and PP-2 classes of protein serine/threonine phosphatase. Ishihara, H., et al. "Calyculin A and okadaic acid: inhibitors of protein phosphatase activity." Biochem. Biophys. Res. Comm. 159: 871-877 (1989).
- Potent non-phorbol type tumor promoter. Suganuma, M., et al. "Calyculin A, an inhibitor of protein phosphatases, a potent tumor promoter on CD-1 mouse skin." Cancer Res. 50: 3521-3525 (1990).
- Please request Technical Note #19 for additional information
- Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.
