S-3400 SB 203580, Free Base, >99%

  • Size
  • US $
  • €
  • £
  • ¥
  • 25 mg
  • 63
  • 56
  • 48
  • 6,900
  • Add to Cart Qty:
  • In stock
  • 50 mg
  • 82
  • 73
  • 62
  • 9,000
  • Add to Cart Qty:
  • In stock
  • 100 mg
  • 147
  • 132
  • 112
  • 16,200
  • Add to Cart Qty:
  • In stock
  • 200 mg
  • 256
  • 230
  • 196
  • 28,200
  • Add to Cart Qty:
  • In stock
  • 500 mg
  • 597
  • 538
  • 458
  • 65,700
  • Add to Cart Qty:
  • In stock
  • 1 g
  • 963
  • 868
  • 739
  • 106,100
  • Add to Cart Qty:
  • In stock

Note: Our Euro, Pound, and Yen prices are revised regularly to account for currency exchange rate fluctuations.

To receive a Formal Quotation for catalog sizes of this product and/or any other products, please add them to your shopping cart and click on the “REQUEST A QUOTATION” box.
Click Here to Request a Quotation for Larger Quantities Free Shipping and Handling to the U.S. and 33 Other Countries
Compare Quality and Prices — LC Labs vs. Other Suppliers
  • M.W. 377.43
  • C21H16FN3OS
  • [152121-47-6]
  • M.I. A

Storage: Store at or below -20 ºC. Solubility: Soluble in DMSO at 100 mg/mL; soluble in ethanol at 12.5 mg/mL with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-50 µM; buffers, serum, or other additives may increase or decrease the aqueous solubil.

Select Lot Number to view Certificate of Analysis

View the SDS for this product

  • More than 1,000 labs worldwide have purchased SB 203580 from LC Labs (either directly from us or from our many distributors, many of whom resell under their own labels).
  • Important, highly specific inhibitor of the kinase known variously as p38, p40, CSBP, or RK. This kinase is a homolog of MAP kinase. Gallagher, T.F., et al. "2,4,5-Triarylimidazole inhibitors of Il-1 biosynthesis." Bioorg. Med. Chem. Lett. 5: 1171-1176 (1995). Cuenda, A., et al. "SB203580 is a specific inhibitor of MAP kinase homologue which is stimulated by cellular stresses and interleukin-1." FEBS Lett.. 364: 229-233 (1995). Hazzalin, C.A., et al. "Effects of the inhibition of p38/RK MAP kinase on induction of five fos and jun genes by diverse stimuli." Oncogene 15: 2321-2331 (1997).
  • Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.
277