Tuesday 17 May 2022 - 15:56
Reminder: Genuine LC Laboratories® brand PMA, which we have been manufacturing in the U.S. for more
than 40 years, is available directly from us: Cat No. P-1680 Phorbol 12-Myristate 13-Acetate, >99.5%.
Our PMA is also available from our >50 U.S. and international distributors, and from more than a dozen
major biochemical reagent "resellers" (who sell our PMA under their own brand names and labels)
FREE SHIPPING TO THE U.S. AND 32 OTHER COUNTRIES! [Read more].
S-9344 Stauprimide, >99%
Synonyms : [N-Benzoyl-7-oxostaurosporine]

- Size
- US $
- €
- £
- ¥
- 1 mg
- 39
- 37
- 31
- 5,100
- In stock
- 5 mg
- 174
- 166
- 139
- 22,500
- In stock
- 10 mg
- 281
- 268
- 225
- 36,400
- In stock
- 25 mg
- 544
- 519
- 436
- 70,400
- In stock
Note: Our Euro, Pound, and Yen prices are revised regularly to account for currency exchange rate fluctuations.
- M.W. 584.62
- C35H28N4O5
- [154589-96-5]
Storage: Store at or below -20 ºC. Solubility: Soluble in DMSO at 100 mg/mL; very poorly soluble in ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 1-10 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility. Disposal: A.
- Stauprimide increases the efficiency of directed differentiation of mouse and human embryonic stem cells (ESCs). Stauprimide binds to NME2 and inhibits its nuclear localization, thus leading to downregulation of c-Myc. Zhu, S., et al. "A small molecule primes embryonic stem cells for differentiation." Cell Stem Cell 4: 416-426 (2009).
- Stauprimide interacts with NME2, a c-Myc-activating transcription factor that is highly expressed in ESCs. Stauprimide treatment inhibits the nuclear localization of NME2 and downregulates c-Myc, enhances ESC exit from the pluripotent state and enables differentiation. Zaret, K. "Using Small Molecules to Great Effect in Stem Cell Differentiation." Cell Stem Cell 4: 373-374 (2009).
- Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.