S-9344 Stauprimide, >99%

Synonyms : [N-Benzoyl-7-oxostaurosporine]

Prices_reduced
  • Size
  • US $
  • €
  • £
  • ¥
  • 1 mg
  • 39
  • 35
  • 29
  • 4,300
  • Add to Cart Qty:
  • In stock
  • 5 mg
  • 174
  • 156
  • 130
  • 19,000
  • Add to Cart Qty:
  • In stock
  • 10 mg
  • 281
  • 252
  • 210
  • 30,700
  • Add to Cart Qty:
  • In stock
  • 25 mg
  • 544
  • 488
  • 407
  • 59,400
  • Add to Cart Qty:
  • In stock
  • 100 mg
  • 998
  • 896
  • 747
  • 109,100
  • Add to Cart Qty:
  • In stock

Note: Our Euro, Pound, and Yen prices are revised regularly to account for currency exchange rate fluctuations.

To receive a Formal Quotation for catalog sizes of this product and/or any other products, please add them to your shopping cart and click on the “REQUEST A QUOTATION” box.
Click Here to Request a Quotation for Larger Quantities Free Shipping and Handling to the U.S. and 33 Other Countries
Compare Quality and Prices — LC Labs vs. Other Suppliers
  • M.W. 584.62
  • C35H28N4O5
  • [154589-96-5]

Storage: Store at or below -20 ºC. Solubility: Soluble in DMSO at 100 mg/mL; very poorly soluble in ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 1-10 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility. Disposal: A.

Select Lot Number to view Certificate of Analysis

View the SDS for this product

  • Stauprimide increases the efficiency of directed differentiation of mouse and human embryonic stem cells (ESCs). Stauprimide binds to NME2 and inhibits its nuclear localization, thus leading to downregulation of c-Myc. Zhu, S., et al. "A small molecule primes embryonic stem cells for differentiation." Cell Stem Cell 4: 416-426 (2009).
  • Stauprimide interacts with NME2, a c-Myc-activating transcription factor that is highly expressed in ESCs. Stauprimide treatment inhibits the nuclear localization of NME2 and downregulates c-Myc, enhances ESC exit from the pluripotent state and enables differentiation. Zaret, K. "Using Small Molecules to Great Effect in Stem Cell Differentiation." Cell Stem Cell 4: 373-374 (2009).
  • Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.
288