T-8188 Trametinib, DMSO Solvate, >99%

Synonyms : [GSK1120212] [JTP-74057] [Trametinib]

Related Terms : [Mekinist]

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  • M.W. 693.53
  • C26H23FIN5O4•C2H6OS
  • [1187431-43-1]

Solubility: DMSO.

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View the SDS for this product

  • This research compound is the DMSO solvate form of trametinib; please see the other form of this product, Cat. No. T-8123, Trametinib, Free Base, for further technical information about both of these research compounds.
  • Trametinib dimethyl sulfoxide is the active ingredient in the drug product sold under the trade name Mekinist®.  This drug is currently approved in a least one country for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations.  NOTE:  THE TRAMETINIB SOLD BY LC LABORATORIES FOR RESEARCH IS NOT MEKINIST®, AND IS NOT FOR HUMAN USE.
  • Sold for laboratory or manufacturing purposes only; not for human, veterinary, food, or household use.
  • This product is offered for R&D use in accordance with (i) 35 USC 271(e)+A13(1) in the U.S.; (ii) Section 69.1 of Japanese Patent Law in Japan; (iii) Section 11, No. 2 of the German Patent Act of 1981 in Germany; (iv) Section 60, Paragraph 5b of the U.K. Patents Act of 1977 in the U.K.; (v) Sections 55.2(1) and 55.2(6) and other common law exemptions of Canadian patent law; (vi) Section 68B of the Patents Act of 1953 in New Zealand together with the amendment of same by the Statutes Amendment Bill of 2002; (vii) such related legislation and/or case law as may be or become applicable in the aforementioned countries; and (viii) such similar laws and rules as may apply in various other countries.
  • Not available in some countries; not available to some institutions; not available for some uses.
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